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Grade 3 denotes disordered, exfoliated germ cells with shrunken, pyknotic nuclei and less distinct edges of the seminiferous tubules

Moreover, Both treatment groups showed a noteworthy reduction in MASI score from the baseline (Manfreda et al., 2023)

This effect exceeds what has been observed with GLP-1-only agonists and is attributed to GIP receptor-mediated improvements in hepatic lipid metabolism and insulin sensitivity